Cellpuri - Disposable Cell Concentration Chip
Cellpuri is a disposable chip that enriches cells without the use of centrifugation method. Cells are being separated using the rheological phenomenon inside the microchannels where the cell suspension pass through to filter out waste medium and collect the enriched cells in the outlet.
- User-friendly disposable cell enrichment chip
- Enriches cells more than 20 times in 2 minutes
- Centrifugation-free workflow minimizes cell damage
- All processes are done inside the clean bench
- 95% recovery when cell washing
- Reduces human error as enrichment is automatically processed using the syringe pump
What is Filterless Filter (FLF) Technology?
It is a microfluidic chip-based cell separation and concentration technology developed by Curiosis. Countless micrometer-sized channels inside the chip create a rheological flow that separates, concentrates, and removes particles of a specific size from the solution. Microchannels were strategically designed to isolate cells according to their size where larger cells are directed towards one side whereas smaller cells flow randomly on lateral axis that eventually compile on the other side. FLF technology can be applied to cell enrichment, white blood cell separation, and blood-plasma separation.
Cell enrichment by Cellpuri
Cellpuri efficiently separated HL-60 cells from medium without spinning-down the cells and more than 20-fold enrichment (121.2x10 cells/mL) was observed in HL-60 cells at an initial concentration of 4.9 x 10 cells/mL.
Reduced cell clumping with Cellpuri
Adherent cells, including MCF7 cells, tend to form clumps during the cell passage. But as shown in above images, enrichment using Cellpuri reduces cell clumping while centrifugation pellets the cells and thus increasing the clumping cells.
